Looking for:Is There An Alternative To Prednisone?.Deflazacort--an alternative to prednisolone?
Drugs to replace prednisone -
I am only 34yrs old and worry that this might be something i need to take forever. I heard of the hardening of arteries, the knee replacements etc. I figure with my case of RA as bad as it is and having Fibro as well as a bad case of iron deficiency anemia, that this drug just might be with me forever. My questions today are…. Is there a more safe dose to take for the body long term at my age that can help prevent the long term damage?
My symptoms are more classically asthma-like. Would that prednisone were not so generally ill-advised! Prednisone is an extremely effective anti-inflammatory medicine and, fortunately, anti-inflammatory treatment works for you.
Since the source of your inflammation is unclear, allergy evaluation with skin testing seems warranted. A combination of inhaled steroids and antihistamines drugs that block the action of histamines , which can cause itching, sneezing and watery eyes or antileukotrienes medications that inhibit the action of substances called leukotrienes, which trigger asthma symptoms will probably be extremely effective for you and reduce the need for oral steroids. I cannot live without prednisone. How harmful to my body is this?
I have tried every new asthma medication on the market. Nothing works for long. Only prednisone works. I am sure that there will be long-term effects on my body. I have already been diagnosed with diabetes and high blood pressure. I was told the prednisone was the cause. Will prednisone eventually kill me?
Prednisone is an extremely effective anti-inflammatory medicine. A study in also demonstrated that two doses of dexamethasone are as effective as five days of prednisone in children with asthma exacerbation admitted to the emergency department.
A meta-analysis in concludes that dexamethasone is associated with less vomiting compared to prednisone when used for asthma exacerbations.
Finally, dexamethasone is available in more dosage forms than prednisone. While prednisone is only available as an oral tablet, dexamethasone is available as a tablet or solution, and can be injected via the intravenous, subcutaneous, or intramuscular route. Methotrexate is used as a steroid-sparing agent for many diseases. It is common to use DMARDs like methotrexate to reduce prednisone doses and allow for earlier discontinuation of prednisone.
Methotrexate is considered a steroid-sparing treatment for many forms of arthritis such as giant cell arteritis, juvenile idiopathic arthritis , rheumatoid arthritis, systemic lupus erythematosus, polymyalgia rheumatica, etc. Methotrexate is also commonly used as a steroid-sparing agent in the treatment of uveitis. Methotrexate may be a viable steroid-sparing agent for myasthenia gravis , although azathioprine is better studied and more commonly used for this purpose.
A study demonstrated that patients with myasthenia gravis who are treated with methotrexate had significant improvement in disease activity and reduced prednisone dosages. Two studies demonstrated that lupus patients taking mycophenolate and voclosporin could achieve clinical response while using much lower doses of oral prednisone.
In fact, these two trials had the lowest peak steroid doses and faster steroid tapering than any other lupus nephritis trial. In patients with lupus without renal involvement, mycophenolate was shown to be superior to azathioprine when combined with steroids, and thus may be a better option than azathioprine for reducing prednisone doses.
Mycophenolate can be used to reduce steroid use in many different inflammatory and immune diseases other than lupus. Mycophenolate has similar steroid-sparing effects as methotrexate when used for uveitis. In a head-to-head study comparing mycophenolate and azathioprine for the treatment of pemphigus, patients taking mycophenolate required significantly lower steroid dose to achieve clinical remission compared to patients taking azathioprine.
Mercaptopurine may be a great option to reduce prednisone doses in patients with inflammatory bowel disease. The brand name of mercaptopurine is Purinethol.
Azathioprine is another DMARD that can reduce steroid doses in patients with inflammatory bowel disease. It is often used along with infliximab for this purpose. Azathioprine may also be used to reduce the use of steroids in patients with myasthenia gravis. A study comparing methotrexate and azathioprine in patients with myasthenia gravis demonstrated that both drugs had a similar degree of steroid-sparing effects.
Azathioprine may also be effective at reducing the cumulative steroid dose in patients with giant cell arteritis, although data is mostly limited to case studies. Azathioprine may effectively lower the need for steroids in patients with recurrent pericarditis.
In one study , Leflunomide is an effective steroid-sparing agent for various kinds of arthritis. In a small study, lower steroid doses were required in patients with polymyalgia rheumatica and giant cell arteritis after taking leflunomide. Leflunomide is also an effective steroid-sparing option for patients with pulmonary sarcoidosis. Another lung disease, chronic hypersensitivity pneumonitis cHP , may be treated with leflunomide in some cases. A study showed that leflunomide had a significant steroid-sparing effect—half of the patients discontinued prednisone entirely.
If you prefer to try the liquid diet approach discuss this with our IBD team. For people with IBD affecting the colon who cannot tolerate steroids or wish to avoid them 5-ASA can be considered in some circumstances, but are generally less powerful. For people who can not come off steroids because their symptoms return when they stop treatment biological treatments or immunosuppressants can be considered.
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Are there alternatives to steroids? | IBD Clinic.Top prednisone alternatives and how to switch your Rx
Are there Alternatives to Prednisone for Asthma? | Everyday Health.
Check with your doctor as soon as possible if any of the following side effects occur:Stop taking the best and seek immediate medical attention if any of the known occur:Some people may experience side effects other than those listed. Hazardous with your doctor if you notice any other that worries you while you are pregnant this medication.
Unfortunately you begin using a girl, be sure to inform your pharmacist of any component conditions or allergies you may have, any medications you are being, whether you are pregnant or delay-feeding, and any other mucous facts about your health.
I have chronic asthma and have been on 20 mg of prednisone for more than 20 years. Is there another drug that can replace prednisone for this kind of long-term use? Many people are stuck on prednisone for long periods of time.
Unfortunately, it's unlikely that anything currently available could replace it completely, but some drugs are also sometimes used to reduce dependence on prednisone.
These are very strong drugs as well and must be used with caution, but sometimes they can have good effects when taken in small amounts or as a short-term alternative to prednisone. According to a study published in the July issue of the Journal of Allergy and Clinical Immunologytwo Chinese herbal supplements - ASHMI and FAHF-2 - were seen to have some effects that were similar to those of prednisone on the signs and symptoms of asthma and food allergies, respectively.
Depending on the advice of your doctor, ASHMI might be a supplement you could try to ease both your asthma symptoms and your dependence on prednisone as a long-term therapy. Keep in mind that I am not a doctor and can't diagnose you here or tell you how these options would affect you. Always check with your doctor before taking any medication or herbal remedy. You should know: The answer above provides general health information that is not intended to replace medical advice or treatment recommendations from a qualified healthcare professional.
What can we help you find? Pain Management. March 9, What to Read Next. Start Survey.localhost › blog › prednisone-alternatives. Specific medications in this group include (in no particular order) Flovent, Pulmicort, QVAR, Asmanex, and many others, both brand-name and. Medications such as methotrexate, Arava, the anti-TNF drugs (Enbrel, Humira, Remicade) are all used to try to reduce prednisone. Arthritis. Deflazacort (Calcort--Shire) is an oral corticosteroid licensed for use in adults and children. When deflazacort first became available last year. Methylprednisolone and prednisone are corticosteroids that can have a significant impact on the body. They are effective medications for reducing inflammation. Meet your Best of the Best Pharmacy Award winners! Rheumatic disorders: 0. Staying hydrated helps our bodies clear out toxins.
I'm an asthma sufferer who was diagnosed after developing thyroid disease. I have allergy-induced asthma, and I am allergic to albuterol. My physicians have me take prednisone when I have an attack. Are there any other options for me? I always suffer when I take the steroid. Yes, there are other options for you. Albuterol is a symptom reliever. It relaxes and opens the airways and works within a few minutes to relieve chest tightness and that dry asthma cough.
Albuterol does not treat the inflammation in the lung linings that actually causes the symptoms of asthma , and it does not help prevent symptoms. Specific medications in this group include in no particular order Flovent, Pulmicort , QVAR , Asmanex , and many others, both brand-name and generic. These are medicines that are similar to prednisone, but the dose is much lower than prednisone taken by mouth, and the side effects are dramatically reduced.
Inhaled corticosteroids work because the medicine is delivered directly to the lung. Another type of controller medication, which is different from either albuterol or steroids, are the pills for asthma, Accolate zafirlukast and Singulair montelukast.
These medications are taken orally each day, and treat inflammation in the lungs. They are usually given to people who need a little more treatment beyond a steroid inhaler. These medicines do not have the side effects of prednisone , and they are generally not as strong as prednisone either.
But they work well for some people. Please talk to your PCP about trying something to control your asthma symptoms. You certainly do have options.
A week or 10 days of small doses of prednisone is like a magic bullet. All asthma symptoms completely disappear, only to return gradually after a month or so. What is implied when asthma symptoms are so responsive to prednisone - does it mean that the symptoms are more allergy-based? I don't manifest allergic symptoms like runny nose or itchiness.
My symptoms are more classically asthma-like. Would that prednisone were not so generally ill-advised! Prednisone is an extremely effective anti-inflammatory medicine and, fortunately, anti-inflammatory treatment works for you. Since the source of your inflammation is unclear, allergy evaluation with skin testing seems warranted.
A combination of inhaled steroids and antihistamines drugs that block the action of histamines , which can cause itching, sneezing and watery eyes or antileukotrienes medications that inhibit the action of substances called leukotrienes, which trigger asthma symptoms will probably be extremely effective for you and reduce the need for oral steroids. I cannot live without prednisone. How harmful to my body is this?
I have tried every new asthma medication on the market. Nothing works for long. Only prednisone works. I am sure that there will be long-term effects on my body. I have already been diagnosed with diabetes and high blood pressure.
I was told the prednisone was the cause. Will prednisone eventually kill me? Prednisone is an extremely effective anti-inflammatory medicine. Unfortunately, there are many side effects associated with it, the most common being osteoporosis , or weakening of the bones. Prolonged steroid use also puts you at increased risk for cataracts , glaucoma , fluid retention , frequent infections, weight gain, skin problems, and mood disorders.
Oral steroids like prednisone should only be used as maintenance medication in the most severe cases of asthma. There are many excellent treatments for asthma , including a variety of inhaled steroids, which are the cornerstone of modern asthma therapy. Keep working with your asthma specialist. It would be prudent for you to be re-evaluated to see if a combination of the existing remedies helps with your symptoms and allows you to cut back on the prednisone.
You may also benefit by working with an allergist to identify potential asthma triggers , both inside and outside the home. A careful examination of your living and working environments may be in order, once you know more about allergens. Many asthma triggers can be eliminated or avoided, and in your case this would be time and effort well spent.
I have chronic severe asthma and I have attacks every morning. I have recently stopped taking high doses of prednisone, which I took for 14 years straight. I do not want to take prednisone anymore. I want to know how to prevent these really scary attacks - any ideas? You should follow up with your physician so that he or she can discuss with you the numerous asthma controller medications such as inhaled corticosteroids, long-acting bronchodilators, leukotriene modifiers, mast cell stabilizers, methylxanthines, anti-IgE therapy if appropriate and possibly others that are currently available and will hopefully eliminate or at least minimize your need for prednisone.
Learn more in the Everyday Health Asthma Center. Health Conditions A-Z. Health Tools. See All. DailyOM Courses. By Dr. Anna Feldweg. Reviewed: July 6,